Biomed Environ Mass Spectrom 1988;15(8):413-417. https://doi.org/10.1186/s40816-020-00234-4, DOI: https://doi.org/10.1186/s40816-020-00234-4. PDF Effects of Ethanol Leaf Extract of Justicia Carnea on Biochemical It creates the perfect environment for aphids and dried sod. Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. The roots and the leaves possess medicinal values and have been used in treating several diseases. When there is high cholesterol level in your blood, LDL- and VLDL- cholesterols are being deposited on the arterial wall of blood vessels, thereby blocking free flow of blood and increasing blood pressure. statement and 10.9734/ijbcrr/2020/v29i630194. The antidiabetic effect of justicia is through the inhibition of-amylase and -glucosidase, the carbohydrate metabolizing enzymes, and also through its hypolipidemic potential. This is . Total reaction mixture of 3ml contained 2.95ml of 0.05M sodium carbonate buffer (pH10.2), 0.02ml tissue sample and 0.03ml of epinephrine (2mM) in 0.005N HCl was used to initiate the reaction. 1999;9:18. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). Correspondence to J Ethnopharmacol. Walters DM., Cho Hye-Youn, Kleeberger SR. Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2. van Andel T., Carvalheiro LG. The findings back up local assertions that they can be. Yes my readers. It is an awesome plant and worth your time and attention. The changing faces of glutathione, a cellular protagonist. Section of livers and kidneys were excised and fixed in 10% formalin for histopathology examination. Nutritive properties of aqueous extract Justicia carnea leaves and its It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . Two of the most important soil considerations include fertility and drainage. A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. Toxicity studies of medicinal plants used in sub-Saharan Africa. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. The aim of this study is to evaluate the effects of J. carnea leaf extract on hematology indices and organ antioxidant system in healthy wistar rats. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. The Portal triad (blue arrow) composed of the hepatic vein and artery as well as the bile duct (PT), the well distributed hepatocytes (H) (yellow arrow) and hepatic sinusoids (black arrow) are demonstrated across study groups. Radhika J, Sathya S, Jothi G, Japasheba JL. Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. Olaniyan JM, Hadiza LM, Hussaini AM, Musa BB, Abubakar SA. The significant decrease in kidney GSH at 1200mg/kg could be due to ample dietary bioactive constituents in the extract that requires frequent conjugation of GSH in the cell or oxidation to oxidized glutathione (GSSG). Decoction of ewe eje or its leaf extract can lower serum cholesterol and get rid of bad cholesterol (LDL). Niger J Physiol Sci. Several medicinal plants such as Xylopia aethiopica [25], Tectona grandis [26] and extracts of M. indica, A. hybridus and T. occidentalis [27] have also been reported to elevate RBC, hemoglobin and packed cell volume. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. 1. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. Due to the local availability, easy access and relatively low cost, medicinal plants are gaining attentions in health care programmes. This also helps prevent self-seeding, which normally takes up a lot of the plants energy at the expense of flowering. Evid Based Complement Alternat Med. Clin Phytosci 2019; 5:9. https://doi.org/10.1186/s40816-019-0104-4. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Background: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Bottom Line. Article ID 687197, 2013; p. 13. https://doi.org/10.1155/2013/687197. Star Apple: Amazing Health Benefits of eating its fruits. The non significant decrease observed in this study is in consonance with the work of Onyeabo et al., [9] who also reported no significant difference in the relative weights of liver and kidney. Tissues were stained with haematoxylin and eosin, mounted on glass slides and examined under a standard light microscope. Canadian J Appl Sci. PubMed Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. Locklear, T. D., Huang, Y., Frasor, J., Doyle, B. J., Perez, A., Gomez-Laurito, J., and Mahady, G. B. Estrogenic and progestagenic effects of extracts of Justicia pectoralis Jacq., an herbal medicine from Costa Rica used for the treatment of menopause and PMS. Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. and M.Sc. Rats were further observed for extended hours of 48h to see if mortality would occur. Water your plants deeply during growth periods, allowing the soil to dry . In this study, the aqueous leaf extract of Justicia carnea was used. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. Hepatic and renal damage has been recently linked with the use of medicinal plants in the treatment of various diseases [5, 6]. Aim. A cup of ewe eje extract in the morning will provide you with energy needed to pull through the days activities. Biomed Res. View abstract. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. Generic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. Ewe eje is safe and healthy for consumption. It does not tolerate low temperatures at all. Kone WM, Koffi AG, Bomisso EL, Tra Bi FH. View abstract. In this study, the aqueous leaf extract of Justicia carnea was used. The spread is equally glorious and can take up 12 15 inches of space. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. The leaves are also rich source of vitamin A, vitamin C, and vitamin E. Another plant with this composition is pumpkin fruit. degree in Biochemistry fromUniversity of Ado-Ekiti, Ekiti State, Nigeria and University of Ibadan, Nigeriarespectively. The resultant liquid after boiling is usually crimson red. Phytother Res 2011;25(3):444-450. Keep an eye out for glasshouse red spider mite and glasshouse whitefly. Note this is the default cart. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. https://doi.org/10.13040/IJPSR.0975-8232. They also maintain our skin tone and texture, and help in reproductive functions. Acta Scientiarum Polonorum, Technologia Alimentaria. For a few weeks, the cutting should be watered every day to promote root development. Nunes TRS, Cordeiro MF, Beserra FG, et al. Side effects of Ewe eje (Justicia carnea leaf Side Effects) Ewe eje is safe and healthy for consumption. The gradual decrease in the weight of organs following short-term exposure of J. carnea leaf ethanol extract may be attributed to adaptive response of the organs arising from daily dosage of the extract or its metabolites within their body. While graded doses of J. carnea ethanol extract showed no significant difference in the liver and kidney GSH compared to the control, only rats that received 1200mg/kg body weight JCEE statistically decreased in the kidney. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. There are several nutritional benefits of justicia carnea leaves. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. In a reaction mixture containing 0.01M phosphate buffer (pH7.0), 0.5ml of 0.2M H2O2 and 0.4ml distilled water, 0.5ml of sample was added. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. However, further research needs to done to determine the mode of action of the plant, and it's effects on humans. Generally disease free. 7 Potential Health Benefits Of Justicia Carnea (Ewe Eje) It is also composed of vitamins and minerals good for heart health. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). J Nat Prod 1988;51(4):804-805. The plants cannot be propagated with seeds. READ ALSO: How long does it take for Aju mbaise to work. Research reports it isnt capable of causing kidney and liver damage either but dont eat it raw. 2023 BioMed Central Ltd unless otherwise stated. Ogwu obara can act as a blood tonic for women during menstruation. SOD is involved in the dismutation of the highly reactive superoxide anion to molecular oxygen (O2) and to less reactive hydrogen peroxides (H2O2) species, whereas CAT removes hydrogen peroxide (H2O2) and toxic hydroxyl radical into water molecule [35]. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Watering depends on humidity and temperature. The result from the kidney histology could be due to the presence of active secondary metabolites and daily dosing of the extract. When you boil the plant, it turns the water red. 2003;84:99104. Consumption of medicinal plants without scrutinizing its efficacy and safety can result in unexpected toxic effects resulting in physiology changes of different organs in the body. Phytochemical screening and Gas Chromatography-Mass Spectrometry (GC-MS) analysis indicated presence of . One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. To create additional collections, you must be a paid member of our site. I also conduct research on molecular basis of human diseases, linking the pharmacological properties of certain natural products and their mechanisms of actions to the treatment of such diseases. Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea. Oyenihi OR, Brooks NL, Oguntibeju OO. Liver and kidney are the main targets of toxicants because they are respectively involved in biotransformation and excretion of xenobiotics. It also increases good cholesterol levels. Mr. T.S. The red coloration of the decoction made people think that the plant must contain blood boosting compounds. Cardioprotective role of Justicia traquebareinsis Linn. In this article i will take you through the nutritional and medicinal benefits of justicia carnea. PubMedGoogle Scholar. In some areas, the plant may tolerate temperatures as low as 50 degrees Fahrenheit (10 C). Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. The ability of glutathione to regenerate these dietary antioxidants has been linked to the redox state of glutathione disulphide-glutathione couple (GSSG/GSH) ratio [31]. As declared by all authors, no competing interests exist. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. The results of this study suggests that ethanol extract of J. carnea leaf is relatively safe, could be beneficial in alleviating hematology related abnormalities without causing adverse effects on endogenous antioxidant system. 2008; 10:2. 1. 3 The plants in the family are reported to have CNS effects which are exploited in the management of epilepsy, other mental disorders, headache and fever, probably due to their sedative and analgesic properties. The liver and kidneys were excised and rinsed immediately in a normal saline (0.9% Nacl) to remove blood stain, dried between layers of Whatman filter paper, weighed and homogenized to obtain the supernatant for biochemical analysis.